Rosa is now head of the Alcantara clan. Scared and scarred, she flees from Sicily to New York to consider her future. There she encounters the American branch of the rival Carnevare Mafia family, also Panthera Arcadians. Forcibly injected with a serum that temporarily prevents her metamorphosis, Rosa is pursued by the Panthera in a deadly chase. Narrowly escaping with her life, Rosa returns to Sicily and to Alessandro, head of the Carnevare clan and Rosa's lover.